- ￥1125 - 1875
- HuaBio/华安生物
- 华安生物
- ER1913-36
- 2025年10月29日
- WB, IHC-P
- Rabbit
- Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Guinea pig
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- 详细信息
- 技术资料
- 免疫原：
KLH conjugated synthetic peptide derived from human mu Opioid receptor 165-270/400
- 亚型：
IgG
- 形态：
Liquid
- 克隆性：
Rabbit polyclonal Antibody
- 标记物：
Non-conjugated
- 适应物种：
Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Guinea pig
- 库存：
现货
- 供应商：
华安生物
- 宿主：
Rabbit
- 应用范围：
WB, IHC-P
- 浓度：
1 mg/mL.
- 抗体名：
mu Opioid receptor
- 规格：
50μl/100μl
| 规格： | 50μl | 产品价格： | ￥1125.0 |
|---|---|---|---|
| 规格： | 100μl | 产品价格： | ￥1875.0 |
-
概述
- 产品描述Receptor for endogenous opioids such as beta-endorphin and endomorphin. Agonist binding to the receptor induces coupling to an inactive GDP-bound heterotrimeric G-protein complex and subsequent exchange of GDP for GTP in the G-protein alpha subunit leading to dissociation of the G-protein complex with the free GTP-bound G-protein alpha and the G-protein beta-gamma dimer activating downstream cellular effectors. The agonist- and cell type-specific activity is predominantly coupled to pertussis toxin-sensitive G(i) and G(o) G alpha proteins, GNAI1, GNAI2, GNAI3 and GNAO1 isoforms Alpha-1 and Alpha-2, and to a lesser extend to pertussis toxin-insensitive G alpha proteins GNAZ and GNA15. They mediate an array of downstream cellular responses, including inhibition of adenylate cyclase activity and both N-type and L-type calcium channels, activation of inward rectifying potassium channels, mitogen-activated protein kinase (MAPK), phospholipase C (PLC), phosphoinositide/protein kinase (PKC), phosphoinositide 3-kinase (PI3K) and regulation of NF-kappa-B. Also couples to adenylate cyclase stimulatory G alpha proteins. The selective temporal coupling to G-proteins and subsequent signaling can be regulated by RGSZ proteins, such as RGS9, RGS17 and RGS4.
- 产品名称Anti-mu Opioid receptor antibody
- 分子量45 KDa
- 种属反应性Human,Mouse,Rat,Dog,Pig,Cow,Rabbit,Guinea Pig
- 验证应用WB,IHC-P
- 抗体类型兔多抗
- 免疫原KLH conjugated synthetic peptide derived from human mu Opioid receptor 165-270/400
- 偶联Non-conjugated
-
性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
- 存储缓冲液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 亚型IgG
- 纯化方式Protein A affinity purified.
- 亚细胞定位Cell membrane; Multi-pass membrane protein. Isoform 12: Cytoplasm.
- 数据链接SwissProt: P35372 Human
- 其它名称
- LMOR
- MOR 1
- mor
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mu Opioid receptor
￥1125 - 1875
