- 详细信息
- 技术资料
- 免疫原:
KLH conjugated synthetic peptide derived from human BCAT1 321-386/386
- 亚型:
IgG
- 形态:
Liquid
- 克隆性:
Rabbit polyclonal Antibody
- 标记物:
Non-conjugated
- 适应物种:
Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep
- 库存:
现货
- 供应商:
华安生物
- 宿主:
Rabbit
- 应用范围:
WB, IHC-P
- 浓度:
1 mg/mL.
- 抗体名:
BCAT1
- 规格:
50μl/100μl
| 规格: | 50μl | 产品价格: | ¥1125.0 |
|---|---|---|---|
| 规格: | 100μl | 产品价格: | ¥1875.0 |
Branched chain amino acid transaminase 1 is a protein that in humans is encoded by the BCAT1 gene. It is the first enzyme in the Branched-chain amino acid (BCAA) degradation pathway and facilitates the reversible transamination of BCAAs and glutamate. BCAT1 resides in the cytoplasm, while its isoform, BCAT2, is found in the mitochondria. This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids (BCKAs) to the branched-chain amino acids (BCAAs) Valine, Leucine and Isoleucine, which are essential for cell growth. In humans, its primary role is the deamination of BCAAs, as humans lack the enzymes for de novo synthesis of BCKAs. The respective cofactors are alpha-ketoglutarate and glutamate. Cells can further degrade BCKAs by the Branched-chain keto acid dehydrogenase complex from which the carbon backbones of each BCAA may enter distinct degradation pathways. The oncogenic transcription factor Myc is frequently reported to drive BCAT1 expression.
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BCAT1
¥1125 - 1875






