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- 文献和实验
- 技术资料
- 免疫原:
Synthetic peptide within C-terminal human CD43.
- 亚型:
IgG
- 形态:
Liquid
- 克隆性:
Rabbit polyclonal Antibody
- 标记物:
Non-conjugated
- 适应物种:
Human
- 库存:
现货
- 供应商:
华安生物
- 宿主:
Rabbit
- 应用范围:
WB,ICC,IHC-P,FC
- 浓度:
1mg/mL
- 抗体名:
DOG1
- 规格:
50μl/100μl
| 规格: | 50μl | 产品价格: | ¥1125.0 |
|---|---|---|---|
| 规格: | 100μl | 产品价格: | ¥1875.0 |
ANO1 (anoctamin 1), also known as DOG1, ORAOV2, TAOS2 or TMEM16A, is a 986 amino acid multi-pass membrane protein that localizes to both the cell membrane and the cytoplasm and belongs to the anoctamin family. Expressed in a variety of tissues with highest expression in liver, gastrointestinal muscle and skeletal muscle, ANO1 functions as a calcium-activated chloride channel that is required for normal tracheal development. Human ANO1 shares 90% sequence identity with its mouse counterpart, suggesting a conserved role between species. ANO1 is present in breast, pancreatic, gastric, and uterine cancers, as well as in neck, ovarian and parathyroid tumors, suggesting a role for ANO1 in carcinogenesis. Three isoforms of ANO1 exist due to alternative splicing events.
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文献和实验相关实验
的抗体分子或片段,但由线状噬菌体表达更为方便有效。M13、fd、F1等噬菌体的外壳蛋白由5种蛋白组成:pⅢ、pⅥ、pⅦ、pⅧ和pⅨ。每种含量不一,其中pⅧ含量最多,每个噬菌体有2700个pⅧ亚基,其余4种蛋白仅5个拷贝。增加噬菌体外壳蛋白的长度并不影响噬菌体的装配,抗体以融合蛋白的形式表达于噬菌体表面。噬菌体表达质粒常用的有fd-CAT1、fd-tet-DOG1、PHEN1、pComb3和pComb3H等。抗体融合蛋白构建多用pⅢ和pⅧ,pⅧ拷贝数高,低亲和力的抗体蛋白容易筛选出来。 在噬菌
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DOG1
¥1125 - 1875






