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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Synthetic peptide within mouse CACNA1C aa 802-851 / 2,139.
- 亚型:
IgG
- 形态:
Liquid
- 克隆性:
Rabbit polyclonal Antibody
- 标记物:
Non-conjugated
- 适应物种:
Human, Mouse, Rat
- 库存:
现货
- 供应商:
华安生物
- 宿主:
Rabbit
- 应用范围:
Dot Blot,ICC,IHC-P,FC
- 浓度:
1 mg/mL.
- 抗体名:
CACNA1C
- 规格:
50μl/100μl
| 规格: | 50μl | 产品价格: | ¥1125.0 |
|---|---|---|---|
| 规格: | 100μl | 产品价格: | ¥1875.0 |
Pore-forming, alpha-1C subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents. Mediates influx of calcium ions into the cytoplasm, and thereby triggers calcium release from the sarcoplasm. Plays an important role in excitation-contraction coupling in the heart. Required for normal heart development and normal regulation of heart rhythm. Required for normal contraction of smooth muscle cells in blood vessels and in the intestine. Essential for normal blood pressure regulation via its role in the contraction of arterial smooth muscle cells. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group (Probable).
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文献和实验相关实验
miR-328的实验犬及miR-328转基因小鼠均表现出房颤易感增强、L型钙离子通道电流减弱及心房肌动作电位时程缩短等心颤表型,而采用micrOFFTM antagomir-328抑制miR-328的作用或敲除内源的miR-328则能逆转这些现象。该研究还揭示,miR-328在房颤中的功能可能是通过其靶标基因CACNA1C和CACNB1实现的。 实验方法与结果: miR-328转基因小鼠或野生型小鼠连续三天尾静脉
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CACNA1C
¥1125 - 1875








