- ￥1125 - 1875
- HuaBio/华安生物
- 华安生物
- EM1712-11
- 2025年07月26日
- WB, FC
- Mouse
- Human, Rat, Monkey
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- 详细信息
- 技术资料
- 免疫原：
Purified recombinant fragment of human SETD7 (AA: 107-366) expressed in E. Coli.
- 亚型：
IgG2a
- 形态：
Liquid
- 克隆性：
Mouse monoclonal Antibody
- 标记物：
Non-conjugated
- 适应物种：
Human, Rat, Monkey
- 库存：
现货
- 供应商：
华安生物
- 宿主：
Mouse
- 应用范围：
WB, FC
- 浓度：
1 mg/mL
- 抗体名：
SETD7
- 规格：
50μl/100μl
| 规格： | 50μl | 产品价格： | ￥1125.0 |
|---|---|---|---|
| 规格： | 100μl | 产品价格： | ￥1875.0 |
Histone methyltransferase that specifically monomethylates Lys-4 of histone H3. H3 Lys-4 methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates Lys-189 of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates Lys-372 of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation.
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SETD7
￥1125 - 1875
