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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Purified recombinant fragment of human BMPR2 expressed in E. Coli.
- 亚型:
IgG1
- 形态:
Liquid
- 克隆性:
Mouse monoclonal Antibody
- 标记物:
Non-conjugated
- 适应物种:
Human, Mouse, Rat, Monkey
- 库存:
现货
- 供应商:
华安生物
- 宿主:
Mouse
- 应用范围:
WB,ICC,IHC-P
- 浓度:
2 mg/mL.
- 抗体名:
BMPR2
- 规格:
50μl/100μl
| 规格: | 50μl | 产品价格: | ¥1125.0 |
|---|---|---|---|
| 规格: | 100μl | 产品价格: | ¥1875.0 |
Members of the transforming growth factor βsuperfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine/threonine kinases and associate to form a signaling complex. Two type I receptors have been characterized, BMPR-IA (also designated SKR5, ALK-3, and BRK-1) and BMPR-IB (also designated ALK-6 and SKR 6), that bind to bone morphogenetic proteins (BMP)-2, BMP-4, and osteogenic protein (OP)-1 (also designated BMP-7). BMPR-IA and BMPR-IB are both expressed in human glioma cell lines. The type II receptor, BMPR-II, efficiently binds to OP-1 and BMP-2 and weakly binds BMP-4, and it is widely expressed in different tissues, including brain (1,5,6). The BMP receptor family members are thought to mediate distinct effects on gene expression, cell differentiation, and morphogenesis in a dose dependent fashion.
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文献和实验相关实验
Delivery of DNA to Pulmonary Endothelium Using Adenoviral Vectors
of the new discoveries concerning the genetic basis of primary pulmonary hypertension (PPH) (1 ). In brief, mutations in the bone morphogenetic protein receptor type 2 (BMPR2, a member of the transforming growth factor-β [TGF-β] family of receptors) gene
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BMPR2
¥1125 - 1875







