- ￥1125 - 1875
- HuaBio/华安生物
- 华安生物
- EM1708-78
- 2025年07月17日
- WB, IHC-P, FC
- Mouse
- Human
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- 详细信息
- 技术资料
- 免疫原：
Recombinant protein
- 亚型：
IgG1
- 形态：
Liquid
- 克隆性：
Mouse monoclonal Antibody
- 标记物：
Non-conjugated
- 适应物种：
Human
- 库存：
现货
- 供应商：
华安生物
- 宿主：
Mouse
- 应用范围：
WB, IHC-P, FC
- 浓度：
2 mg/mL.
- 抗体名：
PIWIL4
- 规格：
50μl/100μl
| 规格： | 50μl | 产品价格： | ￥1125.0 |
|---|---|---|---|
| 规格： | 100μl | 产品价格： | ￥1875.0 |
PIWIL4 (PIWI-like protein 4), also known as HIWI2 is a 852 amino acid protein that belongs to the argonaute family. PIWIL4 contains one PAZ domain and one PIWI domain and is essential for the maintenance of germline stem cells. PIWIL4 is a cytoplasmic protein that is expressed in adult testis. It regulates spermatogenesis and primordial germ cell production and has an essential role in meiotic differentiation of spermatocytes and in self-renewal of spermatogonial stem cells. PIWIL4-null mice are of normal size and weight and have the expected life span. Homozygous PIWIL4-null females are fertile and have no obvious defects. However, PIWIL4-deficient males are infertile and show a meiotic progression defect in early prophase of meiosis I and progressive loss of germ cells with age. Mutant males show elevated expression of LINE-1 and intracisternal A particle (IAP) element transcripts in germ cell lineages. The gene encoding PIWIL4 maps to human chromosome 11.
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PIWIL4
￥1125 - 1875
