3-碘-1H-咪唑-1-甲酸叔丁酯,tert-Butyl 3

Synthesis of Peptide‐Oligonucleotide Conjugates by Diels‐Alder Cycloaddition in Water

) N α ‐(9‐Fluorenylmethoxycarbonyl)‐protected amino acids (Fmoc‐aa‐OH; Novabiochem, Bachem): e.g., for sequences illustrated here, Arg(Pbf), Gly, Leu, Phe, Ser(t Bu), and Tyr(t Bu) (t Bu: tert ‐butyl; Pbf

Biotinylation of a Propargylated Cyclic (3′‐5′) Diguanylic Acid and of Its Mono‐6‐Thioated Analog Under “Click” Conditions

) N 2 ‐Isobutyryl‐5′‐O ‐(4,4′‐dimethoxytrityl)‐2′‐O ‐propargyl‐3′‐O ‐[(N,N ‐diisopropylamino) 2‐cyanoethyloxyphosphinyl]guanosine ( 3 , ChemGenes) 5.5 M tert ‐butyl

Two‐Step, One‐Pot Synthesis of Inosine, Guanosine, and 2′‐Deoxyguanosine O6‐Ethers via Intermediate O6‐(Benzotriazol‐1‐yl) Derivatives

Imidazole, 99% pure (Sigma) tert ‐Butyldimethylsilyl chloride (TBDMS‐Cl), 98% pure (Acros) Hexanes, ACS grade (Fisher