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文献和实验PEGPEI Copolymers for Oligonucleotide Delivery to Cells and Tissues
compounds that markedly improve the in vitro and in vivo delivery of AOs to cells and tissues. By varying the Mw of PEI, as well as the nature of PEG shielding, PEG-PEI-AO nanoparticulates can be prepared with a dynamic range of size, surface charge
Chromosome Orientation Fluorescence In Situ Hybridization or Strand-Specific FISH
the absolute 5′-to-3′ direction of a DNA sequence relative to the short arm-to-long arm axis of the chromosome, and so was originally termed “COD-FISH” (Chromosome Orientation and Direction FISH). CO-FISH has been employed to detect chromosomal inversions
CO-FISH, COD-FISH, ReD-FISH, SKY-FISH
within a chromosome (Goodwin and Meyne, Cytogenet Cell Genet 63:126–127, 1993). In combination with a suitable reference probe, CO-FISH can also determine the absolute 5′–3′ direction of a DNA sequence relative to the short arm (pter) to long arm (qter) axis
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