- ￥8151
- Agrisera
- 瑞典
- AS09 491
- 2025年07月14日
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
上海经科化学科技有限公司
- 抗体英文名：
PIP2;1, PIP2;2, PIP2;3 | Plasma membrane intrinistic protein 2-1,2-2,2-3
- 规格：
100ul
| Immunogen |
| KLH-conjugated synthetic peptide derived from Arabidopsis thaliana PIP2 proteins: AtPIP2-1, At3g53420 , AtPIP2-2 P43287, At2g37170 , AtPIP2-3 P30302, At2g37180 |
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Host Rabbit
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Clonality Polyclonal
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Purity Serum
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Format Lyophilized
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Quantity 100 µl
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Reconstitution For reconstitution add 100 µl of sterile water.
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Storage Store lyophilized/reconstituted at -20°C; make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tubes.
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Tested applications ELISA (ELISA), Western blot (WB)
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Recommended dilution 1 : 8000 (ELISA), 1 : 1000 (WB)
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Expected | apparent MW
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| 30.4 | 28 (PIP2-1,PIP2-2,PIP2-3) kDa |
名称：PIP2;1, PIP2;2, PIP2;3 | Plasma membrane intrinistic protein 2-1,2-2,2-3
货号：AS09 491
品牌：Agrisera
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文献和实验PKC系统(protein kinase C system，PKC system)
由于该系统中的第二信使是磷脂肌醇,故此这一系统又称为磷脂肌醇信号途径(phosphatidylinositol signal pathway)。 在这一信号转导途径中,膜受体与其相应的第一信使分子结合后，激活膜上的Gq蛋白(一种G蛋白),然后由Gq蛋白激活磷酸脂酶Cβ (phospholipase Cβ, PLC), 将膜上的脂酰肌醇4,5-二磷酸(phosphatidylinositol biphosphate, PIP2)分解为两个细胞内的第二信使：二酰甘油
phosphatidylmositol 4,5bis-phosphate (PIP2 ) in a precessive manner (i.e., the enzyme can “scoot” over the surface, hydrolyzing many PIP2 molecules before desorbing from the membrane). Third, membrane binding increases the probability that protein kinase C (PKC
phosphotyrosine interactions bring PI3K in close proximity to its substrate at the plasma membrane and relieve the inhibitory action of p85 on the p110 catalytic subunit, which is then free to convert PtdIns(4,5)P2 (PIP2) into PtdIns(3,4,5)P3 (PIP3). Alternatively
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