Histone H3-like centromeric protein HTR12 replaces formal H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. It is required for the assembly of kinetochore proteins, mitotic progression and chromosome segregation. Localized at centromeres in both m itotic and meiotic cells. Synonymes: CENH3
immunogen
KLH-conjugated synthetic peptide derived from N-terminal domain of Arabidopsis thaliana HTR12AT1G01370 (Q8RVQ9)
host
rabbit
clonality
polyclonal
purity
serum
format
lyophilized
quantity
100 µl
reconstitution
For reconstitution add 100 µl of sterile water.
storage
store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes. Store reconstituted antibodies at 4°C.