动物暴露染毒系统

产品介绍 

动物暴露染毒系统为染毒舱和监控系统分体式设计，用于大小鼠、兔子、猴子等全身暴露染毒，暴露染毒舱尺寸可定制。

 

产品特点

染毒舱采用铝合金框架， 四周为透明PMMA材质， 方便观察；

可选配不锈钢材质；

具有通风换气功能， 保证动物的氧供应， 防止C02及异昧积累：

内置风扇混匀器， 保证舱内气溶胶浓度一致：

集成化传感器舱模块， 全方位监控。

 

染毒舱（型号：WBC-M）

容积180L， 

外尺寸：700×580×620mm; 

可容纳大号大鼠笼2个或中号大鼠笼4个：

其他尺寸可定制。

 

配置比例

动物暴露染毒系统（型号：WBE-B)

• 染毒舱

• 气溶胶发生器 （种类自选-干粉、液体气溶胶发生器、香烟烟雾发生器、柴油尾气发生器......)

• 染毒监控系统z监测温度、 湿度、 氧气、 二氧化碳气源及流量调节系统

• 废气处理系统

• （选配）气溶胶浓度监测、 粒径分布检测等

 

型号选择

 

名称	型号	说明	单位
全身暴露染毒系统	WBE-B-WDF-M	用于干粉型、 PM2. 5颗粒物暴露	套
全身暴露染毒系统	WBE-B-NSF-M	用于液体气溶胶暴露	套
全身暴露染毒系统	WBE-B-CSM-M	用于香烟烟气暴露	套
全身暴露染毒系统	WBE-B-CY-M	用于柴油尾气暴露	套

 

参考文献

[1]Jushan Zhang,Mo Xue,Rong Pan, Yujie Zhu,Zhongyang Zhang, Haoxiang Cheng, Johan L M Björkegren, Jia Chen, Zhiqiang Shi,Ke Hao"An e-cigarette aerosol generation, animal exposure and toxicants quantification system to characterize in vivo nicotine kinetics in arterial and venous blood"[J].bioRxiv preprint doi.

[2]Wenchuan Qi,Lu Liu,Qian Zeng, Ziyang Zhou,Daohong Chen,Bin He,Siyao Gong,Lei Gao,Xiao Wang,Jian Xiong,Dingjun Cai,Shuguang Yu,Ling Zhao，Contribution of cuproptosis and Cu metabolism-associated genes to chronic obstructive pulmonary disease,[J].J Cell Mol Med. 2023;00:1–11.

[3]Guolin Zhao,William Ho,Jinxian Chu, Xiaojian Xiong, Bin Hu,Kofi Oti Boakye-Yiadom,Xiaoyang Xu,Xue-Qing Zhang,Inhalable siRNA Nanoparticles for Enhanced Tumor-Targeting Treatment of KRAS-Mutant Non-Small-Cell Lung Cancer,[J]ACS Applied Materials&Interfaces,2023-06-24,DOI:10.1021/acsami.3c05007.

[4]Liu X, Zhao L, Wang R, et al. TRPM2 exacerbates airway inflammation by regulating oxidized-CaMKⅡ in allergic asthma[J]. Heliyon, 2024, 10(1): e23634.

[5]Tian X, Gao Y, Ma W, et al. Establishment of an Inhalation Administration Non-invasive Murine Model for Rapidly Testing Drug Activity against Mycobacterium tuberculosis[J]. bioRxiv, 2024: 2024.02. 27.582260.

[6]Liu L, Tang Z, Zeng Q, et al. Transcriptomic Insights into Different Stimulation Intensity of Electroacupuncture in Treating COPD in Rat Models[J]. Journal of Inflammation Research, 2024: 2873-2887.

[7]Dong Y, Dong Y, Zhu C, et al. Targeting CCL2-CCR2 signaling pathway alleviates macrophage dysfunction in COPD via PI3K-AKT axis[J]. Cell Communication and Signaling, 2024, 22(1): 364.

[8]Shen S, Huang Q, Liu L, et al. GATA2 downregulation contributes to pro-inflammatory phenotype and defective phagocytosis of pulmonary macrophages in chronic obstructive pulmonary disease[J]. Aging (Albany NY), 2024, 16(19): 12928.

[9]Zou X, Huang Q, Kang T, et al. An integrated investigation of mitochondrial genes in COPD reveals the causal effect of NDUFS2 by regulating pulmonary macrophages[J]. Biology Direct, 2025, 20(1): 4.

[10]Tian X, Gao Y, Li C, et al. A novel non-invasive murine model for rapidly testing drug activity via inhalation administration against Mycobacterium tuberculosis[J]. Frontiers in Pharmacology, 2025, 15: 1400436.

[11]Liu K, Liu R, Zhang C, et al. Suzi Daotan Decoction alleviates asthmatic airway remodeling through the AMPK/SIRT1/PGC-1α signaling pathway and PI3K/AKT signaling pathway[J]. Scientific Reports, 2025, 15(1): 6690.

[12]Huang Q, Kang T, Shen S, et al. Extracellular vesicular delivery of ceramides from pulmonary macrophages to endothelial cells facilitates chronic obstructive pulmonary disease[J]. Cell Communication and Signaling, 2025, 23(1): 124.

[13]Zeng H, Liu X, Liu P, et al. Exercise's protective role in chronic obstructive pulmonary disease via modulation of M1 macrophage phenotype through the miR-124-3p/ERN1 axis[J]. Science Progress, 2025, 108(3): 00368504251360892.

 

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*此介绍及参数为产品基础信息，可能滞后于产品更新，具体参数请与我司联系。