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MCE 国际站:Microbial Metabolite Library
Nature has been a source of medicinal products for millennia, with many useful active substances developed from plant sources. In the 20th century, the discovery of the penicillin was the starting point for drug discovery from microbial sources. Microorganisms, which have been considered to be a rich source of unique bioactive compounds, play an important role in the development of the chemistry of natural products and medical therapy. Microbial metabolites have proved to be affective antimicrobial agents, anti-tumor agents, enzyme inhibitors, anti-inflammatory agents, etc. Today, many microbial-originated antibiotics are available in the mark, and a large number of bioactive metabolites are used in medicine. MCE provides a unique collection of 568 microbial metabolites, which is an important source of lead compounds and can be used for drug discovery.
Description & Advantages:
• A unique collection of 568 microbial metabolites for high throughput screening (HTS) and high content screening (HCS).
• All compounds derived from microbes with better bioavailability.
• A useful tool for microbial metabolites-related drug discovery.
• Bioactivity and safety confirmed by preclinical research and clinical trials. Some compounds have been approved by FDA.
• Structurally diverse, bioactive, and cell permeable.
• More detailed compound information with structure, IC50, and brief introduction.
• High purity and quality validated by NMR and LC/MS.
• All compounds are in stock and continuously updated.