N,N-dimethyl(1H-pyrrolo[2,3-b]

Convenient and Efficient Approach to the Permanent or Reversible Conjugation of RNA and DNA Sequences with Functional Groups

  Figure 4.52.15 Fluoride‐assisted conversion of 2′‐ O ‐pyrenylated ribonucleosides (S.11 a‐d ) to native ribonucleosides. Abbreviations: TBAF, tetra‐ n ‐butylammonium fluoride; B, uracil‐1‐yl, cytosin‐1‐yl

Biotinylation of a Propargylated Cyclic (3′‐5′) Diguanylic Acid and of Its Mono‐6‐Thioated Analog Under “Click” Conditions

Figure 14.9.1 Synthesis of the propargylated dinucleoside phosphate triester 5 . Abbreviations: DMTr, 4,4′‐dimethoxytrityl; Lev, levulinyl; TBDMS, tert ‐butyldimethylsilyl; GiBu , 2‐( N ‐isobutyryl)guanin‐9‐yl. Adapted with permission

ICON Probes: Synthesis and DNA Methylation Typing

Introduction Basic Protocol 1: Synthesis of N‐(2‐Aminoethyl) (4′‐Methyl‐2,2′‐Bipyridine‐4‐yl)Hexanamide Basic Protocol 2: Synthesis of a Bipyridine‐Modified Adenosine Phosphoramidite Basic