Rebastinib is an orally bioavailable tyrosine kinase inhibitor that inhibits Abl1 (IC50 = 0.8 nM) as well as the gatekeeper mutant Abl1T315I (IC50 = 4 nM) and the activation loop mutant Abl1H396P.{34442} It also inhibits the Src family kinases Src, Lyn,
英文名:
DCC-2036
库存:
1 mg, 10 mg, 25 mg, 5 mg
供应商:
Cayman
CAS号:
1020172-07-9
规格:
This biochemical is available in the following size(s) 10 mg, 25 mg, 5 mg - Please inquire
An orally bioavailable tyrosine kinase inhibitor that inhibits Abl1 (IC50 = 0.8 nM), Abl1T315I (IC50 = 4 nM), and Abl1H396P; also inhibits the Src family kinases Src, Lyn, Fgr, and Hck and the tyrosine kinases KDR, FLT3, and Tie2 at nanomolar concentrations