AN2728 is a boron-based, topical anti-inflammatory agent that inhibits phosphodiesterase 4 (PDE4; IC50 = 0.11 µM).{33611} It is less potent against PDE1A, PDE3A, and PDE7A (IC50s = 6.12, 6.41, and 0.73 µM, respectively).{33611} AN2728 suppresses the rel
英文名:
Crisaborole
库存:
100 mg, 25 mg, 250 mg, 50 mg
供应商:
Cayman
CAS号:
906673-24-3
A selective PDE4 inhibitor (IC50 = 0.11 µM); suppresses the release of the proinflammatory cytokines TNF-α, IL-2, INF-γ, IL-5, and IL-10 (IC50s = 0.50, 0.59, 0.72, 2.25, and 2.58 µM, respectively)