4-IPP is an inhibitor of macrophage migration inhibitory factor (MIF).{59363} It acts as a suicide substrate for MIF, leading to covalent modification of the N-terminal proline required for activation of its catalytic activity. 4-IPP (10 and 100 µM) inh
库存:
10 mg, 25 mg, 5 mg, 50 mg
供应商:
Cayman
CAS号:
41270-96-6
A MIF inhibitor; a suicide substrate for MIF; inhibits the migration and anchorage-independent growth of A549 NSCLC cells; inhibits proliferation of, and induces apoptosis in, TPC-1 cells at 50 and 100 µM; inhibits MIF tautomerase activity in mouse liver in vivo at 50 mg/kg