9-Methoxyellipticine is an alkaloid and a derivative of the DNA intercalating agent ellipticine (Item No. 18742) that has been found in O. maculata and has anticancer activity.{60369,60370} It intercalates into DNA and is an inhibitor of wild-type c-Kit
规格:
This biochemical is available in the following size(s) 25 mg, 5 mg - Please inquire
An alkaloid with anticancer activity; intercalates into DNA; an inhibitor of wild-type c-Kit and c-KitD816V (IC50s = 0.8 and 0.6 µM, respectively); inhibits proliferation of Ba/F3 cells in the presence of SCF and Ba/F3 cells expressing c-KitD816V (IC50s = 0.5 and 0.3 µM, respectively); increases survival in rodent tumor models