Ac-QPKK(Ac)-AMC is a fluorogenic substrate for sirtuin 1 (SIRT1), SIRT2, and SIRT3.{59928} It is selectively deacylated by SIRT1-3 over SIRT6. Upon enzymatic cleavage by SIRT1, SIRT2, or SIRT3, 7-amino-4-methylcoumarin (AMC) is released and its fluoresc
This biochemical is available in the following size(s) 100 mg, 250 mg, 500 mg - Please inquire
A fluorogenic substrate for SIRT1, SIRT2, and SIRT3; AMC is released upon enzymatic cleavage by SIRT1, SIRT2, or SIRT3 and its fluorescence can be used to quantify SIRT1, SIRT2, and SIRT3 activity; ex/em = 340-360/440-460 nm, respectively