PD-1/PD-L1 is an inhibitor of the protein-protein interaction between programmed cell death protein 1 (PD-1) and PD-1 ligand (PD-L1).{30903} It inhibits the PD-1/PD-L1 interaction in a time-resolved FRET (TR-FRET) assay (IC50 = 6-100 nM). PD-1/PD-L1 inh
英文名:
BMS-1|Programmed Cell Death 1/Programmed Cell Death-Ligand 1 Inhibitor 1
库存:
1 mg, 10 mg, 25 mg, 5 mg
供应商:
Cayman
CAS号:
1675201-83-8
A PD-1/PD-L1 interaction inhibitor; inhibits the PD-1/PD-L1 interaction in a TR-FRET assay (IC50 = 6-100 nM); reduces LPS-induced increases in PD-1 levels and apoptosis in MH-S mouse alveolar macrophages at 1 µM; surgical neointimal patching with PD-1/PD-L1-coated patches decreases neointimal thickness and inflammatory cell accumulation in a rat model of patch angioplasty