MMP-13 Inhibitor is a pyrimidine dicarboxamide that inhibits matrix metalloproteinase-13 (MMP-13, also known as collagenase-3) with an IC50 value of 8 nM.{32009,32010} MMP-13 Inhibitor binds to pockets that are unique to MMP-13, rather than the catalyti
A pyrimidine dicarboxamide that selectively inhibits MMP-13 (IC50 = 8 nM); blocks osterix-dependent calcification of matrices in limb bud cells during endochondral ossification