BGJ398 is an orally available inhibitor of human FGFRs (IC50s = 0.9, 1.4, and 1 nM for FGFR1, FGFR2, and FGFR3, respectively).{31102,30600} It inhibits FGFR4 and VEGFR2 with IC50 values of 60 and 180 nM, respectively, and displays comparatively little
英文名:
NVP-BGJ398|Infigratinib
库存:
1 mg, 10 mg, 25 mg, 5 mg
供应商:
Cayman
CAS号:
872511-34-7
规格:
This biochemical is available in the following size(s) 10 mg, 25 mg, 5 mg - Please inquire
A pan FGFR inhibitor (IC50s = 0.9, 1.4, and 1 nM for FGFR1, FGFR2, and FGFR3, respectively); suppresses proliferation of cancer cells with wild-type FGFR3 overexpression and in an RT112 bladder cancer xenograft mouse model overexpressing wild-type FGFR3