4E1RCat is an inhibitor of the eIF4F translation initiation complex that blocks eIF4E:eIF4G and eIF4E:4E-BP1 interactions.{31602} It has been shown to prevent the assembly of the eIF4F complex and to inhibit cap-dependent translation with an IC50 value
英文名:
eIF4E/eIF4G Interaction Inhibitor II
库存:
1 mg, 10 mg, 5 mg
供应商:
Cayman
CAS号:
328998-25-0
An inhibitor of the eIF4F translation initiation complex that inhibits cap-dependent translation with an IC50 value of ~4 μM; reverses tumor chemoresistance in a mouse model of lymphoma by sensitizing cells to the proapoptotic action of DNA damage