The Ras family of small GTPases (H-Ras, K-Ras, and N-Ras) function as molecular switches, cycling between a GTP-bound active state and a GDP-bound inactive state, to turn on downstream Raf protein kinases. This initiates complex signaling pathways involv
库存:
1 mg, 10 mg, 25 mg, 5 mg
供应商:
Cayman
CAS号:
2061344-88-3
规格:
This biochemical is available in the following size(s) 1 mg, 10 mg, 5 mg - Please inquire
An allosteric inhibitor of oncogenic K-Ras(G12C); disrupts both switch-I and switch-II, altering the native nucleotide preference to favor GDP over GTP, which impedes binding to Raf