Cdk4 inhibitor is a cell-permeable, asymmetrical indolocarbazole that exhibits antiproliferative activity by blocking cyclin D1/Cdk4 with an IC50 value of 0.8 μM.{28945} It is selective for cyclin D1/Cdk4, demonstrating 7-fold and 28-fold weaker activit
英文名:
Cyclin-dependent kinase 4 Inhibitor
库存:
1 mg, 5 mg, 500 µg
供应商:
Cayman
CAS号:
546102-60-7
规格:
This biochemical is available in the following size(s) 25 mg, 50 mg, 500 mg - Please inquire
A cell-permeable, asymmetrical indolocarbazole that exhibits antiproliferative activity by selectively blocking cyclin D1/Cdk4 (IC50 = 0.8 μM); inhibits HCT116 and NCI-H460 tumor cell growth (IC50s 1 cell cycle arrest