The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis.{22577} BGP-15 is a PARP inhibitor and insulin sensitizer. In perfused heart, it blocks self-ADP-ribosylation of nuclear PARP (Ki = 57 µM) and mono-A
库存:
1 mg, 10 mg, 25 mg, 5 mg
供应商:
Cayman
CAS号:
66611-37-8
规格:
This biochemical is available in the following size(s) 10 mg, 25 mg, 5 mg - Please inquire
A PARP inhibitor and insulin sensitizer; blocks self-ADP-ribosylation of nuclear PARP (Ki = 57 µM) and mono-ADP-ribosylation of GRP78; acts as a co-inducer of Hsp72, augmenting expression induced by Hsf1 in adipocytes and skeletal muscles and improving insulin sensitivity