11β-Prostaglandin F2α (11β-PGF2α) is the primary metabolite of PGD2 (Item No. 12010).{57057} It is formed from PGD2 via the NADPH-dependent aldo-keto reductase PGF synthase (PGFS; Item No. 10007940) in the liver or lung.{57058} 11β-PGF2α induces contra
英文名:
11-epi PGF2α|11β-PGF2α|9α,11β-PGF2α
库存:
1 mg, 10 mg, 5 mg
供应商:
Cayman
CAS号:
38432-87-0
规格:
This biochemical is available in the following size(s) 1 g, 100 mg, 250 mg - Please inquire
The primary PGD2 metabolite; formed from PGD2 via PGFS in the liver or lung; induces contraction of isolated cat iris sphincter (EC50 = 0.045 µM); induces contraction of isolated human bronchial smooth muscle from 0.1-30 µM; induces ERK and CREB phosphorylation, as well as increases the viability of MCF-7 breast cancer cells stably expressing the FP receptor at 0.1 and 1 µM