O6-Alkylguanine-DNA alkyltransferase (AGT, also known as methylguanine DNA methyltransferase, or MGMT) is a DNA repair protein that directly removes alkyl groups located on the O6-position of guanine from DNA, restoring DNA integrity in a single step.{26
英文名:
NSC 637037
库存:
1 g, 10 mg, 250 mg, 50 mg
供应商:
Cayman
CAS号:
19916-73-5
A guanine analog with antineoplastic activity; irreversibly inactivates AGT, with 40% reduction in alkyltransferase activity achieved at 0.06 µM with recombinant human AGT; effective in vivo as well as in vitro