ATP citrate lyase (ACL) catalyzes the synthesis of acetyl-CoA and oxaloacetate using citrate, CoA, and ATP as substrates and Mg2+ as a cofactor.{27878} The ACL-dependent synthesis of acetyl-CoA is important for the de novo synthesis of fatty acids and ch
库存:
10 mg, 25 mg, 5 mg, 50 mg
供应商:
Cayman
CAS号:
943962-47-8
A cell-permeable ACL inhibitor (IC50 = 0.13 µM) that has been reported to reduce weight gain and lower plasma cholesterol, triglycerides, and glucose in a mouse model of hyperlipidemia