Pifithrin-α (Item No. 13326) is an inactivator of p53 that blocks p53-dependent transcriptional activation and apoptosis.{17259} p-nitro-Pifithrin-α is a cell-permeable analog of pifithrin-α.{23578} It blocks p53-mediated expression of p21/WAF1 and apop
英文名:
p-nitro-PFT-α
库存:
1 mg, 10 mg, 25 mg, 5 mg
供应商:
Cayman
CAS号:
389850-21-9
A cell-permeable analog of pifithrin-α that blocks p53-mediated expression of p21/WAF1 and apoptosis in cortical neurons ten-fold more potently than pifithrin-α; suppresses p53-mediated TGF-β1 expression in human proximal tubular cells and attenuates steatosis and liver injury in mice fed a high-fat diet