Ac-IEPD-AMC is a fluorogenic substrate for granzyme B.{48137} Upon enzymatic cleavage by granzyme B, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify granzyme B activity. AMC displays excitation/emission maxima of
This biochemical is available in the following size(s) 500 µg - Please inquire
A fluorogenic substrate for granzyme B; AMC is released upon enzymatic cleavage by granzyme B and its fluorescence can be used to quantify granzyme B activity; ex/em = 340-360/440-460 nm, respectively