Ac-VDVAD-pNA is a colorimetric substrate for caspase-2.{7213} Caspase-2 binds to and cleaves the Val-Asp-Val-Ala-Asp (VDVAD) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of ca
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A colorimetric caspase-2 substrate; cleavage of the VDVAD peptide sequence releases pNA, which can be quantified by colorimetric detection at 405 nm as a measure of caspase-2 activity; can also be cleaved, with lower efficiency, by caspase-3 and -7