Tazobactam is a β-lactamase inhibitor with greater activity against Ambler class A serine penicillinases and class C cephalosporinases, including TEM-1, SHV-1, and P99 (IC50s = 97, 150, and 8.5 nM, respectively) than class B metallo-β-lactamases and the
英文名:
CL-298741|YTR 830H
库存:
1 g, 5 g, 500 mg
供应商:
Cayman
CAS号:
89786-04-9
规格:
This biochemical is available in the following size(s) 1 mg, 10 mg, 5 mg - Please inquire
A β-lactamase inhibitor; inhibits Ambler class A serine penicillinases and class C cephalosporinases, including TEM-1, SHV-1, and P99 (IC50s = 97, 150, and 8.5 nM, respectively) and the class D oxacillinase OXA-2 (IC50 = 10 nM); active against Gram-positive (MIC90s = 2-128 µg/ml) and Gram-negative bacteria (MIC90s = 4-128 µg/ml) when used in combination with piperacillin; potentiates the activity of ceftolozane against Enterobacteriaceae in a neutropenic mouse model of thigh infection