(±)-Methoxyverapamil is a phenylalkylamine L-type calcium channel blocker and methoxy derivative of verapamil (Item No. 14288).{38991} (±)-Methoxyverapamil blocks recombinant rat L-type calcium channels expressed in tsA201 cells with IC50 values of 782
英文名:
Gallopamil|NSC 274966
库存:
10 mg, 25 mg, 5 mg, 50 mg
供应商:
Cayman
CAS号:
16662-46-7
A phenylalkylamine L-type calcium channel blocker; blocks recombinant rat L-type calcium channels expressed in tsA201 cells (IC50s = 782 and 8,000 nM at holding potentials of 10 and -60 mV, respectively); blocks maitotoxin-induced calcium influx in NIH3T3 fibroblast cells (IC50 = 16 μM); inhibits histamine-induced acid secretion by primary enriched guinea pig parietal cells (IC50 = 10.9 μM); binds to rat myocardial membranes (IC50 = 16 nM); inhibits electrically-stimulated contractions in rat right myocardial ventricular strips (EC50 = 1.95 μM); decreases blood pressure and inhibits uterine contractions in conscious, ovariectomized, post-partum rats (204 and 324 μg/kg, respectively)