Thiothixene is a typical antipsychotic.{39485} It selectively binds to dopamine D2 over D1, D3, and D4 receptors (Kis = 0.417, 338, 186.2, and 363.1 nM, respectively). Thiothixene also binds to various serotonin (5-HT), histamine H1, α1- and α2-adrenerg
英文名:
cis-Thiothixene|CP 12,252-1|NSC 108165|P 4657B
库存:
1 mg, 5 mg
供应商:
Cayman
CAS号:
5591-45-7
规格:
This biochemical is available in the following size(s) 5 mg - Please inquire
A typical antipsychotic; selectively binds to dopamine D2 over D1, D3, and D4 receptors (Kis = 0.417, 338, 186.2, and 363.1 nM, respectively); binds to various 5-HT, histamine H1, α1- and α2-adrenergic, muscarinic acetylcholine, and sigma receptors (Kis = 15-5,754 nM) as well as the dopamine, norepinephrine, and serotonin transporters (Kis = 3.16-30 μM); reduces spontaneous and amphetamine-induced locomotor activity in rats; enhances latent inhibition in rats; increases competitive behavior in submissive mice