The Myc proto-oncogenes interact with Max to form a dimer that regulates gene transcription. The protein c-Myc, in particular, promotes gene expression relevant to cell growth and thus drives cancer. 10058-F4 is a cell-permeable thiazolidinone that inhib
库存:
10 mg, 25 mg, 5 mg, 50 mg
供应商:
Cayman
CAS号:
403811-55-2
A cell-permeable inhibitor of the dimerization of c-Myc and Max at 64 µM, preventing c-Myc-dependent gene expression and cell proliferation; induces cell cycle arrest, apoptosis, and myeloid differentiation at 100 µM in human acute myeloid leukemia cells; inhibits the nuclear Myc protein, N-Myc, at 50 µM