A 9-amino acid peptide that dilates blood vessels and consequently reduces blood pressure by inducing the release of prostacyclin, nitric oxide, and endothelium-derived hyperpolarizing factor; also contracts non-vascular smooth muscle in the bronchus
供应商:
Cayman
规格:
This biochemical is available in the following size(s): 10 mg, 25 mg, 5 mg, 50 mg – Please inquire
Bradykinin is a 9-amino acid peptide that dilates blood vessels and consequently reduces blood pressure by inducing the release of prostacyclin, nitric oxide, and endothelium-derived hyperpolarizing factor.{9662,9836,8073} It also contracts non-vascular smooth muscle in the bronchus and gastrointestinal tract, increases vascular permeability, and is involved in the mechanism of pain mediation.{17695,4496,9663} The discovery of bradykinin-potentiating peptides from snake venom led to the discovery of a class of highly-effective anti-hypertensive drugs, the ACE inhibitors, which have been shown to prevent angiotensin-converting enzyme’s inactivation of bradykinin.{25197}