STA-21 is a natural antibiotic that potently inhibits STAT3 by preventing its dimerization and DNA binding when used at concentrations of 20-30 μM.{24347} It blocks the growth and survival of cancer cells that express constitutively active STAT3 (e.g.,
英文名:
Ochromycinone
库存:
1 mg, 5 mg, 500 µg
供应商:
Cayman
CAS号:
28882-53-3
Potently inhibits STAT3 by preventing its dimerization and DNA binding at concentrations of 20-30 μM; blocks the growth and survival of cancer cells that express constitutively active Stat3 (e.g., DU145 cells, IC50 = 12.2 μM); prevents the proliferation of human keratinocytes and has value in improving psoriasis