Glutamate, the major excitatory neurotransmitter in the brain, acts on both ionotropic and metabotropic glutamate receptors. Excessive metabotropic glutamate receptor (mGluR) transmission has been linked to epilepsy, ischemia, pain, anxiety, and depress
库存:
1 mg, 10 mg, 5 mg, 50 mg
供应商:
Cayman
CAS号:
1186195-60-7
A negative allosteric modulator of the mGlu5a receptor subtype (Ki = 42 nM; IC50 = 110 nM); produces antidepressant, and anxiolytic effects