PSI-6130 is a nucleoside inhibitor of the NS5B RNA polymerase of hepatitis C virus (HCV; Ki = 4.3 µM).{48516} It inhibits HCV genotype 1b (GT-1b) Con1 and GT-1a H77 viral replication in Huh7 replicon cells using a luciferase-based assay (EC50s = 0.51 an
库存:
1 mg, 5 mg
供应商:
Cayman
CAS号:
817204-33-4
规格:
This biochemical is available in the following size(s) 10 mg, 25 mg, 5 mg - Please inquire
A nucleoside inhibitor of the NS5B RNA polymerase of HCV (Ki = 4.3 µM); inhibits HCV genotype 1b (GT-1b) Con1 and GT-1a H77 viral replication in Huh7 replicon cells using a luciferase-based assay (EC50s = 0.51 and 0.30 µM, respectively); inhibits replication of HCV GT-1b and GT-1a replicons from clinical isolates, with EC50 values ranging from 0.60 to 1.41 µM, and 0.20 to 0.43 µM, respectively, in the same assay; has little or no activity against WNV, DV, HIV, or HBV (EC90s = 46.3, >100, >100, and >10 µM, respectively)