The group IVA phospholipase A2 (PLA2), known as calcium-dependent cytosolic PLA2 (cPLA2), selectively releases arachidonic acid (AA) from membrane phospholipids, playing a central role in initiating the synthesis of prostaglandins (PGs) and leukotrienes
库存:
1 mg, 10 mg, 5 mg, 500 µg
供应商:
Cayman
CAS号:
341973-06-6
Reversible, selective inhibitor of cPLA2 with an IC50 value of 4.2 nM in enzyme assays; potently blocks the release of AA and the production of PGE2 and LTC4 in cells (IC50 = 24, 25, and 14 nM, respectively)