Prostaglandin E2 (PGE2) activates four E prostanoid (EP) receptors, EP1-4. EP4 is a Gs protein-coupled receptor that, by elevating the second messenger cAMP, plays important roles in bone formation and resorption, cancer, and atherosclerosis.{16772,1677
库存:
1 mg, 10 mg, 5 mg, 500 µg
供应商:
Cayman
CAS号:
346673-06-1
A very potent agonist of EP4, binding with a Ki value of 1.2 nM; does not bind EP1, EP2, EP3, DP, FP, IP, or TP receptors