Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds which selectively inhibit PTKs of key growth factors.{14963} AG-879 i
英文名:
Tyrphostin AG-879
库存:
10 mg, 25 mg, 5 mg, 50 mg
供应商:
Cayman
CAS号:
148741-30-4
规格:
This biochemical is available in the following size(s) 1 mg, 100 µg, 500 µg - Please inquire
A tyrphostin compound that inhibits nerve growth factor (NGF)-dependent TrkA tyrosine phosphorylation in PC-12 cells (IC50 = ~40μM), HER2-ErbB2 kinase in several breast and ovarian cancer cell lines (IC50 = ~0.5 μM), and the VEGF receptor FLK1 (IC50 = ~1 μM)