Onalespib is a selective inhibitor of Hsp90 (IC50 = 18 nM).{18725} It induces the degradation of specific Hsp90 client proteins, including mutant EGFR, for up to seven days in tumor cell lines in vitro and up to three days in vivo.{18725,33082} Onalespi
英文名:
AT-13387
库存:
1 mg, 10 mg, 25 mg, 5 mg
供应商:
Cayman
CAS号:
912999-49-6
A selective inhibitor of Hsp90 (IC50 = 18 nM); induces the degradation of specific Hsp90 client proteins; efficacious in a range of xenograft models