Cyclin-dependent kinases (CDKs) play a key role in regulating cell division by phosphorylating distinct substrates in different phases of the cell cycle. Cell cycle deregulation in many cancers often results from altered CDK activity. Thus, CDKs are pote
库存:
1 mg, 10 mg, 5 mg, 50 mg
供应商:
Cayman
CAS号:
140651-18-9
规格:
This biochemical is available in the following size(s) 10 mg, 25 mg, 5 mg - Please inquire
A potent, selective inhibitor of Cdk9 in vitro (IC50 = 0.35 µM); a competitive inhibitor of Cdk2-cyclin E with respect to ATP, with Ki and IC50 values of 13.3 and 20 µM, respectively