SC-514 is a selective and reversible inhibitor of IκB kinase 2 (IKK2) (IC50 = 3-12 μM) that displays greater than 10-fold selectivity over 28 other kinases, including JNK, p38, MK2, and ERK.{17344,17345} In synovial fibroblasts stimulated with interleuk
英文名:
GK 01140
库存:
10 mg, 25 mg, 5 mg, 50 mg
供应商:
Cayman
CAS号:
354812-17-2
规格:
This biochemical is available in the following size(s) 100 mg, 5 mg, 50 mg - Please inquire
A selective and reversible inhibitor of IKK2 (IC50 = 3-12 μM) that displays >10-fold selectivity over 28 other kinases; attenuates NF-κB-mediated gene expression in synovial fibroblasts, smooth muscle cells, and astrocytes