S-5751 is an antagonist of the prostaglandin D2 (PGD2) receptor DP1 (Ki = 1.6 nM) that shows at least 20-fold selectivity over receptors for thromboxane and prostacyclin, as well as the PGE2 receptor EP2.{12534,32842} Orally administered S-5751 blocks P
库存:
1 mg, 5 mg, 500 µg
供应商:
Cayman
CAS号:
209268-36-0
A selective antagonist of DP1 (Ki = 1.6 nM); blocks PGD2-induced plasma exudation in the conjunctiva (ED50 = 0.099 mg/kg) and suppresses antigen-induced allergic responses in guinea pigs