Matreya,LLC是一家油脂生化公司,提供综合系列的鞘脂、糖脂、神经节苷脂、球三糖神经酰胺、脂肪酸和甾醇。我们在高纯度产品和专门的技术援助方面享有可靠的声誉。 Matreya致力于开发和制造的脂质和生化物质。我们提供高质量的化学合成和天然产物的提取和纯化。惠诚生物把Matreya已经引入到国内市场,大量现货销售及产品服务。 This product is a well-defined ceramide trihexoside containing a hexadecanoic acid acylated to the ceramide moiety making it ideal as an internal standard and for biological studies.1 Ceramide trihexoside (CTH or Gb3) is a glycosphingolipid found mostly in mammalian cell membranes. It is involved in cellular signaling and has been identified as a receptor for various toxins including shiga toxins and shiga-like toxins.2 Some toxins, such as veratoxins from Escherichia coli, require specific fatty acids on the ceramide portion of CTH to show affinity in binding. An accumulation of CTH in the cellular membranes due to a lack of alpha-galactosidase to convert it into lactosyl ceramide results in Fabry disease.3 This product can be used as an excellent standard for the identification of CTH in Fabry disease by HPLC4 and mass spectrometry. An inability to convert CTH to globoside due to mutations in the gene sequence leads to the Pk blood group phenotype. It appears that under certain conditions CTH can enhance anticoagulant activity. CTH has also been studied as a tool to investigate lymphocyte activation.5上海惠诚生物专业优势供应Matreya磷脂类标准品 ,每周三和国外下单,2周到货。更多关于Matreya品牌脂类标准品,欢迎拨打惠诚生物客户服务电话021-60498804