Matreya,LLC是一家油脂生化公司,提供综合系列的鞘脂、糖脂、神经节苷脂、球三糖神经酰胺、脂肪酸和甾醇。我们在高纯度产品和专门的技术援助方面享有可靠的声誉。 Matreya致力于开发和制造的脂质和生化物质。我们提供高质量的化学合成和天然产物的提取和纯化。惠诚生物把Matreya已经引入到国内市场,大量现货销售及产品服务。 Very-long-chain fatty acids (VLCFA) consisting of 26 carbons or more comprise a small but very important group of biological lipids that are found in both plants and animals. There is relatively little known about VLCFA, especially those with more than 30 carbons, and the need for high purity standards to explore their mechanisms and processes is greatly needed. VLCFA are found in small amounts in most animal tissues and are especially abundant in the brain, skin, testis, and some glands, such as the meibomian gland. The recognition of VLCFA in human diseases has recently sparked a renewed interest in the investigation of these crucial compounds. VLCFA are implicated in several diseases and standards for the determination of the lipids associated with these diseases are needed. One of these human diseases, X-linked adrenoleukodystrophy, causes an increase in plasma of VLCFA due to a genetic defect that affects the peroxisomal assembly and contributes to severe pathological changes such as inflammatory responses; This disease can also lead to neurological changes and severe demyelination. Another disease that results in unusually high levels of VLCFA is Zwelleger syndrome which is characterized by a reduced number of, and morphologically-abnormal, peroxisomes.1 In plants VLCFA are converted to long chain hydrocarbons which are used to make waxes that are essential to their survival.2,3 VLCFA acylated to sphingolipids are critical in many biological functions4 and substantial amounts are found to be amide-linked to the long-chain sphingoid base sphinganine, forming a ceramide, which constitutes the lipid backbone of sphingomyelin and other sphingolipids. VLCFA can often be found in esterified linkages with cholesterol, gangliosides, galactocerebrosides, sphingomyelin, and phosphatidylcholine. In myelin VLCFA are important in increasing the structural stability. Lipids are very important in signaling and the influence of VLCFA in signaling needs to be further explored.5 Studies that explore the roles of VLCFA acylated to phospholipids, sphingolipids and glycerolipids or esterified to triglycerides, sterols, and other compounds show great promise in revealing much about the various biological functions of these lipids. If you require VLCFA acylated or esterified to a specific backbone the team at Matreya will be happy to synthesize them for you.上海惠诚生物专业优势供应Matreya磷脂类标准品 ,每周三和国外下单,2周到货。更多关于Matreya品牌脂类标准品,欢迎拨打惠诚生物客户服务电话021-60498804