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CYP2E1 Antibody

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  • ¥2400
  • PLLABS已认证
  • 加拿大
  • 2025年07月09日
  • WB: 1:100-500 IHC: 1:500-1000
  • Rabbit
  • Mo,Rat
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      peptide corresponding to a sequence at the N-terminus of mouse Cytochrome P450 2E1.

    • 亚型

      Rabbit Polyclonal IgG

    • 形态

      液态

    • 保存条件

      保存于-20℃

    • 克隆性

      多克隆

    • 标记物

      无标记(PLlabs可供应生物素、酶、荧光素标记的抗体)

    • 适应物种

      Mo,Rat

    • 保质期

      按说明书条件可保存1-2年

    • 抗原来源

      见详细说明资料

    • 目录编号

      PL0402548

    • 级别

      超纯

    • 库存

      大量

    • 供应商

      华拓生物

    • 宿主

      Rabbit

    • 应用范围

      WB: 1:100-500 IHC: 1:500-1000

    • 浓度

      1mg/ml

    • 靶点

      CYP2E1

    • 抗体英文名

      CYP2E1 Antibody

    • 抗体名

      CYP2E1抗体

    • 规格

      0.1ml

    产品细节图片1
    CYP2E1 Antibody
    Cat#:PL0402548
    Isotype:Rabbit Polyclonal IgG
    Immunogen:peptide corresponding to a sequence at the N-terminus of mouse Cytochrome P450 2E1.
    Purification: Immunogen affinity purified

    Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)

    Background:
    CYP2E1, also known as P450IIE1, is a member of the P450IIE subfamily which is ethanol-inducible. It has at least 1 gene which is mapped to 10q24.3-qter, and a second is likely in rat and in man. Both the rat and human proteins encoded by this gene contain 493 amino acids and calculated molecular masses of 56,634 and 56,916 daltons, respectively. In addition, genetic polymorphisms in the 5-prime flanking region of the human P450IIE1 gene affected its binding of transacting factor and changed its transcriptional regulation, which may lead to interindividual differences of microsomal drug oxidation activity. P450IIE1 is an important enzyme for the catalysis of the conversion of ethanol to acetaldehyde and to acetate in humans,and it is also involved in the metabolism of nitrosamines.
    Alternate Names:
    4-nitrophenol 2-hydroxylase antibody;CP2E1_HUMAN antibody;CPE1 antibody;CYP2E antibody;CYP2E1 antibody;CYPIIE1 antibody;Cytochrome P450 2E1 antibody.
    Specificity Reaction:Mo,Rat
    Application Notes:WB: 1:100-500 IHC: 1:500-1000
    Storage :
    Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.

    This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
    PLlabs公司可供应相应抗体的生物素、辣根过氧化物酶、荧光素(FITC、PE、 CY3、 CY5、 CY7、 PE- CY3/5/7)标记抗体,欢迎大家咨询订购。

    产品细节图片2 产品细节图片3 产品细节图片4
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    图标文献和实验
    相关实验
    • CYP2E1酶联免疫分析

      CYP2E1 酶联免疫分析 试剂盒使用说明书 本试剂仅供研究使用         目的:本试剂盒用于测定人血清,血浆及相关液体样本中 CYP2E1 的含量。 实验原理:   本试剂盒应用双抗体夹心法测定标本中人 CYP2E1 水平。用纯化的人 CYP2E1 抗体包被微孔板,制成固相抗体,往包被单抗的微孔中依次加入 CYP2E1 ,再与 HRP 标记的 CYP2E1 抗体结合,形成抗体 - 抗原 - 酶标抗体复合物,经过彻底洗涤

    • Generation of Antibody Molecules Through Antibody Engineering

      been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional

    • Spectrophotometric Analysis of Human CYP2E1-Catalyzed p-Nitrophenol Hydroxylation

      CYP2E1 is expressed in adult (1 , 2 ) and fetal (3 ) human liver in addition to extrahepatic tissues such as lung and placenta (4 ). Treatment of primary cultures of human hepatocytes with ethanol induces CYP2E1 protein

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